SCHEDULED MAINTENANCE
Nortopsentin D, an antifungal 2,4-diinodolylimidazole, is synthesized by use of a successive and regioselective diarylation, in which N-protected 2,4,5-tri- and 4,5-di-bromoimidazole derivatives are treated with N-silylated 3-indolylboric acid in the presence of a palladium(o) catalyst.
I. Kaswasaki, M. Yamashita and S. Ohta, J. Chem. Soc., Chem. Commun., 1994, 2085 DOI: 10.1039/C39940002085
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