Issue 17, 1994

Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation

Abstract

5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into oligodeoxyribonucleotides.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 1997-1998

Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation

H. Sawai, A. Nakamura, S. Sekiguchi, K. Yumoto, M. Endoh and H. Ozaki, J. Chem. Soc., Chem. Commun., 1994, 1997 DOI: 10.1039/C39940001997

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