Issue 7, 1993

Facile preparation of cyclic oligoribonucleotides

Abstract

A convenient solid-phase synthesis of small cyclic oligoribonucleotides based on elongation of the chain by phosphoramidite chemistry, and successive cyclization of the linear fragments by a phosphotriester approach is described.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1993, 747-749

Facile preparation of cyclic oligoribonucleotides

L. De Napoli, A. Galeone, L. Mayol, A. Messere, G. Piccialli and C. Santacroce, J. Chem. Soc., Perkin Trans. 1, 1993, 747 DOI: 10.1039/P19930000747

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