Issue 3, 1993
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Conversion of (–)-4-hydroxy-2-oxabicyclo[3.3.0]oct-7-en-3-one into the anti-HIV agent carbovir

Rosemary A. MacKeith,   Ray McCague,   Horacio F. Olivo,   Christopher F. Palmer  and  Stanley M. Roberts  

Abstract

The lactone (±)-1 was resolved using Pseudomonas fluorescens lipase and vinyl acetate; the ester (–)-3 obtained by this process was subsequently converted into the anti-HIV agent carbovir (–)-9.

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Article information

DOI
https://doi.org/10.1039/P19930000313
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1993, 313-314

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Conversion of (–)-4-hydroxy-2-oxabicyclo[3.3.0]oct-7-en-3-one into the anti-HIV agent carbovir

R. A. MacKeith, R. McCague, H. F. Olivo, C. F. Palmer and S. M. Roberts, J. Chem. Soc., Perkin Trans. 1, 1993, 313 DOI: 10.1039/P19930000313

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