N,O-Bis-Fmoc (fluoren-9-ylmethoxycarbonyl) derivatives of Nα-(2-hydroxy-4-methoxybenzyl)amino acids 5 are useful intermediates for the preparation of peptides with reversibly protected (tertiary) peptide bonds; their value in inhibiting interchain association during solid phase peptide synthesis is demonstrated.
T. Johnson, M. Quibell, D. Owen and R. C. Sheppard, J. Chem. Soc., Chem. Commun., 1993, 369 DOI: 10.1039/C39930000369
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