Enantioselective halolactonisation of bis-γ,δ-unsaturated carboxylic acid derivatives: use of a sultam and oxazolidine-2-ones as chiral auxiliary
Abstract
Iodolactonisation of heptadienoic acid derivatives 2 and 3 having oxazolidin-2-ones or a sultam as chiral auxiliary gave the chiral iodolactones 4 and 5 in moderate to excellent enantiselectivity.