Issue 9, 1991

Whole cell catalysed kinetic resolution of 6-azabicyclo[3.2.0]hept-3-en-7-one: synthesis of (–)-cispentacin (FR 109615)

Abstract

Enantioselective hydrolysis of the β-lactam (±)-2 using Rhodococcus equi provided (1R,5S)-6azabicyclo[3.2.0] hept-3-en-7-one (+)-2, a precursor of the antifungal agent cispentacin.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1991, 2276-2277

Whole cell catalysed kinetic resolution of 6-azabicyclo[3.2.0]hept-3-en-7-one: synthesis of (–)-cispentacin (FR 109615)

C. Evans, R. McCague, S. M. Roberts, A. G. Sutherland and R. Wisdom, J. Chem. Soc., Perkin Trans. 1, 1991, 2276 DOI: 10.1039/P19910002276

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