One-pot annulation to tricyclo[5.3.1.03,8]undecane-2,6-diones by sequential three-fold Michael reactions. A formal synthesis of (±)-seychellene
Abstract
Lewis acid-assisted triple Michael reactions yield tricyclo[5.3.1.03,8]undecane-2,6-dione derivatives from the trimethylsilyl enol ethers of cyclohex-2-enones and divinyl ketone. The application of this reaction allowed a formal synthesis of (±)-seychellene.