A common synthetic route to the pericarbonyl and perimethylene lignan lactones dimethyl conidendrin and dimethyl retrodendrin
Abstract
An all trans 1-aryl-2-methoxycarbonyl tetralin-3-carboxylic acid synthesised in 32% overall yield can be converted, at will, to either dimethyl conidendrin or dimethyl retrodendrin in one step.