Heterocycles from carbohydrate precursors. Part 40. Kinetic and thermodynamic products of ketalation of 1-C-substituted L-threo-glycerol: a regioselective formation of 1,3-dioxolanes

Abstract

The mode of ketalation of some L-threo-glycerols has been studied. The kinetic product has an α-terminal (dioxolane) ring. The formation of β(dioxane) ring was also detected. The thermodynamic product has an α-threo-(dioxolane) ring. The regioselectivity of the reaction and the structures of the products have been studied.