The intramolecular orthogonal contract of the Tyr and Phe aromatic rings in the solid-state folded conformation of leucine-enkephalin trihydrate confers on this peptide some resemblance to the morphine molecule.
A. Aubry, N. Birlirakis, M. Sakarellos-Daitsiotis, C. Sakarellos and M. Marraud, J. Chem. Soc., Chem. Commun., 1988, 963 DOI: 10.1039/C39880000963
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