Auranthine, a new benzodiazepinone metabolite of Penicillium aurantiogriseum
Abstract
A novel metabolite, auranthine, has been isolated from sporing cultures of Penicillium aurantiogriseum and its structure, 6,7,7a,8-tetrahydroquinazolino[3′,2′:1,6]pyrido[2,3-b][1,4]benzodiazepine-9,16-dione comprising anthranilate and glutamine moieties, has been elucidated from spectral evidence and biosynthetic reasoning.