Oxidation of the title N-aminoquinazolone (2) in dichloromethane in the presence of α-methylene-γ-butyrolactone gave a 1 : 1 : 3 ratio of stereoisomers (3): if the oxidation is carried out in the presence of a small quantity of trifluoroacetic acid (TFA), only one of these stereoisomers in produced in 72% yield.
R. S. Atkinson and G. Tughan, J. Chem. Soc., Chem. Commun., 1986, 834 DOI: 10.1039/C39860000834
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