A spectrophotometric method is described for the determination of tetracycline hydrochloride. The drug is reacted with sodium molybdate at the boiling-point for 15 min in hydrochloric acid medium. The absorbance of the colour developed is measured at 430 nm. The method is simple, reproducible and accurate and is easily applied to the determination of the drug in the pure form and in pharmaceutical preparations.
S. M. Sultan, Analyst, 1986, 111, 97 DOI: 10.1039/AN9861100097
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