The addition of chlorosulphonyl isocyanate to an allenyl acetate. The preparation of a versatile intermediate for antibiotic synthesis
Abstract
Chlorosulphonyl isocyanate and 1-acetoxy-3-methylbuta-1,2-diene react to form 4-acetoxy-3-(1-methylethylidene)azetidinone, a useful presursor to the skeletons of several antibiotics.
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