A monolayer vesicle membrane with a (large) thiosuccinic acid and a (small) sulphonic acid head groups is orientated in such a way that ![[gt-or-equal]](https://www.rsc.org/images/entities/char_2a7e.gif)
98% of the large head groups are on the outside and, correspondingly, 98% of the small head groupsd are inside.
J. Fuhrhop and J. Mathieu, J. Chem. Soc., Chem. Commun., 1983, 144 DOI: 10.1039/C39830000144
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