1,4-Diarylbutanes undergo intramolecular oxidation with vanadium oxytrifluoride to yield dibenzo[a, c]cyclooctenes. Two short synthetic routes to the lignan, (±)-deoxyschizandrin have been developed from 3,4,5-trimethoxypropiophenone.
T. Biftu, B. G. Hazra and R. Stevenson, J. Chem. Soc., Perkin Trans. 1, 1979, 2276 DOI: 10.1039/P19790002276
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