Two types of nucleotides (5) and (6) have been synthesized as key intermediates for fully protected oligoribonucleotides which are suitable for elongation of the chain in the 3′- and 5′-directions by the triester method; condensation of these nucleotides yielded a fully protected dinucleotide [e.g.(7)] in high yield.
E. Ohtsuka, T. Tanaka, T. Wakabayashi, Y. Taniyama and M. Ikehara, J. Chem. Soc., Chem. Commun., 1978, 824 DOI: 10.1039/C39780000824
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