Coproporphyrinogen-III (1) is shown to be converted biochemically into protoporphyrin-IX (4) with loss of one hydrogen atom from each propionate residue on rings A and B and the 3H-tracer results are consistent with a stereospecific process.
A. R. Battersby, J. Baldas, J. Collins, D. H. Grayson, R. J. James and E. McDonald, J. Chem. Soc., Chem. Commun., 1972, 1265 DOI: 10.1039/C39720001265
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