Metal complexes of the virus inhibitor 2-α-hydroxybenzylbenzimidazole

Abstract

The preparation is described of the complexes M(HBB)₃X₂(HBB = 2-α-hydroxybenzylbenzimidazole; M = Co, X = Cl, Br or I; M = Ni, X = Cl, Br, I or ClO₄), M(HBB)₂X₂(M = Co or Ni, X = NO₃ or NCS), M(HBB)₂(NCS)₂(dimethylformamide)₃(M = Co or Ni) and Co(HBB)₃(ClO₄) in which one molecule of the HBB has lost a proton The structures of the compounds are deduced from spectral and magnetic measurements. In most cases the HBB chelates through the tertiary nitrogen of the imidazole ring and the hydroxylic oxygen atom, but monodentate behaviour through nitrogen is also observed.