Jump to main content
Jump to site search

Issue 30, 2015
Previous Article Next Article

Self-healing hydrogels containing reversible oxime crosslinks

Author affiliations

Abstract

Self-healing oxime-functional hydrogels have been developed that undergo a reversible gel-to-sol transition via oxime exchange under acidic conditions. Keto-functional copolymers were prepared by conventional radical polymerization of N,N-dimethylacrylamide (DMA) and diacetone acrylamide (DAA). The resulting water soluble copolymers (P(DMA-stat-DAA)) were chemically crosslinked with difunctional alkoxyamines to obtain hydrogels via oxime formation. Gel-to-sol transitions were induced by the addition of excess monofunctional alkoxyamines to promote competitive oxime exchange under acidic conditions at 25 °C. The hydrogel could autonomously heal after it was damaged due to the dynamic nature of the oxime crosslinks. In addition to their chemo-responsive behavior, the P(DMA-stat-DAA) copolymers exhibit cloud points which vary with the DAA content in the copolymers. This thermo-responsive behavior of the P(DMA-stat-DAA) was utilized to form physical hydrogels above their cloud point. Therefore, these materials can either form dynamic-covalent or physically-crosslinked gels, both of which demonstrate reversible gelation behavior.

Graphical abstract: Self-healing hydrogels containing reversible oxime crosslinks

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 13 Apr 2015, accepted on 23 Jun 2015 and first published on 06 Jul 2015


Article type: Paper
DOI: 10.1039/C5SM00865D
Citation: Soft Matter, 2015,11, 6152-6161
  •   Request permissions

    Self-healing hydrogels containing reversible oxime crosslinks

    S. Mukherjee, M. R. Hill and B. S. Sumerlin, Soft Matter, 2015, 11, 6152
    DOI: 10.1039/C5SM00865D

Search articles by author