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Issue 112, 2015
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3-Hydroxypropionaldehyde (3-HPA) quantification by HPLC using a synthetic acrolein-free 3-hydroxypropionaldehyde system as analytical standard

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Abstract

HPLC-based quantification of 3-HPA using a synthetic acrolein-free 3-HPA standard obtained from commercially available 1,2,4-butanetriol through a straightforward and easy synthetic process has advantages over previous colorimetric methods of easier and safer implementation, and greater specificity. This HPLC method is very simple to implement in a lab, does not need any extra handling of the sample to be analyzed, and is suitable even in the presence of other aldehydes and 3-HPA derivatives, provided that the latter do not have similar retention times.

Graphical abstract: 3-Hydroxypropionaldehyde (3-HPA) quantification by HPLC using a synthetic acrolein-free 3-hydroxypropionaldehyde system as analytical standard

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Publication details

The article was received on 07 Sep 2015, accepted on 20 Oct 2015 and first published on 23 Oct 2015


Article type: Paper
DOI: 10.1039/C5RA18274C
Citation: RSC Adv., 2015,5, 92619-92627
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    3-Hydroxypropionaldehyde (3-HPA) quantification by HPLC using a synthetic acrolein-free 3-hydroxypropionaldehyde system as analytical standard

    G. Burgé, A. L. Flourat, B. Pollet, H. E. Spinnler and F. Allais, RSC Adv., 2015, 5, 92619
    DOI: 10.1039/C5RA18274C

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