Issue 5, 2016

Fluorescent nanoparticles based on AIE fluorogens for bioimaging

Abstract

Fluorescent nanoparticles (FNPs) have recently attracted increasing attention in the biomedical field because of their unique optical properties, easy fabrication and outstanding performance in imaging. Compared with conventional molecular probes including small organic dyes and fluorescent proteins, FNPs based on aggregation-induced emission (AIE) fluorogens have shown significant advantages in tunable emission and brightness, good biocompatibility, superb photo- and physical stability, potential biodegradability and facile surface functionalization. In this review, we summarize the latest advances in the development of fluorescent nanoparticles based on AIE fluorogens including polymer nanoparticles and silica nanoparticles over the past few years, and the various biomedical applications based on these fluorescent nanoparticles are also elaborated.

Graphical abstract: Fluorescent nanoparticles based on AIE fluorogens for bioimaging

Article information

Article type
Review Article
Submitted
28 Jul 2015
Accepted
20 Sep 2015
First published
01 Oct 2015

Nanoscale, 2016,8, 2471-2487

Author version available

Fluorescent nanoparticles based on AIE fluorogens for bioimaging

L. Yan, Y. Zhang, B. Xu and W. Tian, Nanoscale, 2016, 8, 2471 DOI: 10.1039/C5NR05051K

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