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Issue 40, 2015
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An easy-to-prepare mini-scaffold for DNA origami

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Abstract

The DNA origami strategy for assembling designed supramolecular complexes requires ssDNA as a scaffold strand. A system is described that was designed approximately one third the length of the M13 bacteriophage genome for ease of ssDNA production. Folding of the 2404-base ssDNA scaffold into a variety of origami shapes with high assembly yields is demonstrated.

Graphical abstract: An easy-to-prepare mini-scaffold for DNA origami

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Publication details

The article was received on 22 Jul 2015, accepted on 25 Aug 2015 and first published on 17 Sep 2015


Article type: Communication
DOI: 10.1039/C5NR04921K
Citation: Nanoscale, 2015,7, 16621-16624
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    An easy-to-prepare mini-scaffold for DNA origami

    S. Brown, J. Majikes, A. Martínez, T. M. Girón, H. Fennell, E. C. Samano and T. H. LaBean, Nanoscale, 2015, 7, 16621
    DOI: 10.1039/C5NR04921K

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