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Issue 8, 2015
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3D-printed microfluidic automation

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Abstract

Microfluidic automation – the automated routing, dispensing, mixing, and/or separation of fluids through microchannels – generally remains a slowly-spreading technology because device fabrication requires sophisticated facilities and the technology's use demands expert operators. Integrating microfluidic automation in devices has involved specialized multi-layering and bonding approaches. Stereolithography is an assembly-free, 3D-printing technique that is emerging as an efficient alternative for rapid prototyping of biomedical devices. Here we describe fluidic valves and pumps that can be stereolithographically printed in optically-clear, biocompatible plastic and integrated within microfluidic devices at low cost. User-friendly fluid automation devices can be printed and used by non-engineers as replacement for costly robotic pipettors or tedious manual pipetting. Engineers can manipulate the designs as digital modules into new devices of expanded functionality. Printing these devices only requires the digital file and electronic access to a printer.

Graphical abstract: 3D-printed microfluidic automation

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Publication details

The article was received on 02 Feb 2015, accepted on 27 Feb 2015 and first published on 27 Feb 2015


Article type: Paper
DOI: 10.1039/C5LC00126A
Author version available: Download Author version (PDF)
Citation: Lab Chip, 2015,15, 1934-1941
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    3D-printed microfluidic automation

    A. K. Au, N. Bhattacharjee, L. F. Horowitz, T. C. Chang and A. Folch, Lab Chip, 2015, 15, 1934
    DOI: 10.1039/C5LC00126A

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