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Issue 13, 2016
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Updating and further expanding GSK's solvent sustainability guide

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Abstract

GlaxoSmithKline (GSK) has previously reported on the development of a GSK solvent guide, the incorporation of lifecycle impact and the expansion of the guide including a customisable version intended for posting in different business areas. This guide has recently been enhanced by: (1) adding 44 additional solvents, many of which have literature claims to be “green”; (2) adjusting the way in which multiple health, environment, safety, and waste categories are combined to reach a single composite score and colour assignment; (3) updating the data behind all scores, especially toxicology and health hazard assessment, and revising the methodology to reflect current guidelines and data. The full methodology behind this work is hereby shared. The new GSK Solvent Sustainability Guide enables GSK scientists to objectively assess solvents. It facilitates both comparison of individual sustainability criteria, and a composite score and colour for rank ordering, incorporating multiple facets of sustainability.

Graphical abstract: Updating and further expanding GSK's solvent sustainability guide

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Publication details

The article was received on 01 Mar 2016, accepted on 18 Apr 2016 and first published on 18 Apr 2016


Article type: Paper
DOI: 10.1039/C6GC00611F
Citation: Green Chem., 2016,18, 3879-3890
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    Updating and further expanding GSK's solvent sustainability guide

    C. M. Alder, J. D. Hayler, R. K. Henderson, A. M. Redman, L. Shukla, L. E. Shuster and H. F. Sneddon, Green Chem., 2016, 18, 3879
    DOI: 10.1039/C6GC00611F

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