Issue 45, 2021, Issue in Progress
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RSC Advances

Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents†

Andrea Morandini,a   Emanuele Spadati,a   Benedetta Leonetti,b   Roberto Sole, ORCID logo ac   Vanessa Gatto, ORCID logo d   Flavio Rizzolio ORCID logo a  and  Valentina Beghetto ORCID logo *ad  

* Corresponding authors

a Università Ca’ Foscari di Venezia, Via Torino 155, Venezia Mestre, Italy
E-mail: beghetto@unive.it

b Brenta S.r.l. – Nine Trees Group., Viale Milano, 26, 36075 Montecchio Maggiore Vicenza, Italy

c Consorzio Interuniversitario per le Reattività Chimiche e Catalisi (CIRCC), Via C. Ulpiani 27, 70126 Bari, Italy

d Crossing S.r.l., Viale della Repubblica 193/b, Treviso, Italy

Abstract

The first examples of highly efficient antimicrobial triazine-derived bis imidazolium quaternary ammonium salts (TQAS) are reported. TQAS have been prepared with an easy, atom efficient, economically sustainable strategy and tested as antimicrobial agents, reaching MIC values below 10 mg L−1. Distinctively, TQAS have low MIC and low cytotoxicity.

Graphical abstract: Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents

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Article information

DOI
https://doi.org/10.1039/D1RA03455C
Article type
Paper
Submitted
04 May 2021
Accepted
15 Aug 2021
First published
19 Aug 2021
This article is Open Access
Creative Commons BY license

RSC Adv., 2021,11, 28092-28096

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Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents

A. Morandini, E. Spadati, B. Leonetti, R. Sole, V. Gatto, F. Rizzolio and V. Beghetto, RSC Adv., 2021, 11, 28092 DOI: 10.1039/D1RA03455C

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