Issue 2, 2021
From the journal:

Chemical Communications

Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy†

Hongqian Cao,ab   Yang Yang, ORCID logo *b   Minghui Liang, ORCID logo b   Yuntian Ma,b   Nan Sun,c   Xibao Gaoa  and  Junbai Li ORCID logo *c  

* Corresponding authors

a School of Public Health, Shandong University, Jinan, Shandong Province, China

b CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China
E-mail: yangyang@nanoctr.cn

c CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China
E-mail: jbli@iccas.ac.cn

Abstract

Polydopamine nanoparticles were used to stabilize a nano-Pt catalyst to relieve tumour hypoxia in photodynamic therapy (PDT). Polydopamine not only provides a platform for carrying nano-Pt and photosensitizers but is also used as a photothermal reagent for photothermal therapy (PTT). The system presented an enhanced anti-tumor therapy effect through a combined PDT and PTT mechanism.

Graphical abstract: Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy

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Article information

DOI
https://doi.org/10.1039/D0CC07355E
Article type
Communication
Submitted
08 Nov 2020
Accepted
19 Nov 2020
First published
26 Nov 2020

Chem. Commun., 2021,57, 255-258

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Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy

H. Cao, Y. Yang, M. Liang, Y. Ma, N. Sun, X. Gao and J. Li, Chem. Commun., 2021, 57, 255 DOI: 10.1039/D0CC07355E

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