A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular self-assembly†
Abstract
This article presents a new label-free fluorescence assay based on supramolecular self-assembly of cucurbit[7]uril and specific peptide Gly-Pro-Phe-Gly for monitoring DPP4 activity in clinical samples. It also displays a good potential application in high-throughput screening of DPP4 inhibitors.