Issue 4, 2020
From the journal:

Chemical Communications

The interaction of an amorphous metal–organic cage-based solid (aMOC) with miRNA/DNA and its application on a quartz crystal microbalance (QCM) sensor†

Xia Jin,a   Yu-Ping Zhang,a   Dian-Mei Li,a   Ding Ma,a   Sheng-Run Zheng, ORCID logo *a   Chu-Hong Wu,a   Jia-Ying Lia  and  Wei-Guang Zhang*a  

* Corresponding authors

a School of Chemistry, South China Normal University, Guangzhou, China
E-mail: zhengsr-scnu.edu.cn, wgzhang-scnu.edu.cn
Fax: +86-20-39310210

Abstract

The interaction between an aMOC and miRNA/DNA is studied and the use of a signal probe DNA (spDNA)@aMOC complex as an effective amplifier in a QCM sensor to detect miRNA is developed. The signal can be significantly enhanced, which leads to improved performance when detecting and distinguishing miRNAs.

Graphical abstract: The interaction of an amorphous metal–organic cage-based solid (aMOC) with miRNA/DNA and its application on a quartz crystal microbalance (QCM) sensor

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Article information

DOI
https://doi.org/10.1039/C9CC08014G
Article type
Communication
Submitted
13 Oct 2019
Accepted
06 Dec 2019
First published
06 Dec 2019

Chem. Commun., 2020,56, 591-594

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The interaction of an amorphous metal–organic cage-based solid (aMOC) with miRNA/DNA and its application on a quartz crystal microbalance (QCM) sensor

X. Jin, Y. Zhang, D. Li, D. Ma, S. Zheng, C. Wu, J. Li and W. Zhang, Chem. Commun., 2020, 56, 591 DOI: 10.1039/C9CC08014G

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