Issue 87, 2019
From the journal:

Chemical Communications

Stimulus-responsive nanomotors based on gated enzyme-powered Janus Au–mesoporous silica nanoparticles for enhanced cargo delivery†

Antoni Llopis-Lorente,abc   Alba García-Fernández,abc   Elena Lucena-Sánchez,ab   Paula Díez,ab   Félix Sancenón,abc   Reynaldo Villalonga,d   Daniela A. Wilson ORCID logo *e  and  Ramón Martínez-Máñez ORCID logo *abc  

* Corresponding authors

a Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Spain
E-mail: rmaez@qim.upv.es

b Unidad Mixta UPV-CIPF de Investigación en Mecanismos de Enfermedades y Nanomedicina, Valencia, Universitat Politècnica de València, Centro de Investigación Príncipe Felipe, València, Spain

c CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain

d Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain

e Department of Systems Chemistry, Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen, The Netherlands
E-mail: d.wilson@science.ru.nl

Abstract

Here we report functional stimulus-responsive nanomotors based on Janus Au–mesoporous silica nanoparticles capable of self-propelling via the biocatalytic conversion of chemical fuel, that read information from the environment (the presence of glutathione) and accordingly deliver a cargo.

Graphical abstract: Stimulus-responsive nanomotors based on gated enzyme-powered Janus Au–mesoporous silica nanoparticles for enhanced cargo delivery

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Article information

DOI
https://doi.org/10.1039/C9CC07250K
Article type
Communication
Submitted
16 Sep 2019
Accepted
07 Oct 2019
First published
08 Oct 2019

Chem. Commun., 2019,55, 13164-13167

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Stimulus-responsive nanomotors based on gated enzyme-powered Janus Au–mesoporous silica nanoparticles for enhanced cargo delivery

A. Llopis-Lorente, A. García-Fernández, E. Lucena-Sánchez, P. Díez, F. Sancenón, R. Villalonga, D. A. Wilson and R. Martínez-Máñez, Chem. Commun., 2019, 55, 13164 DOI: 10.1039/C9CC07250K

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