Issue 3, 2019

Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols

Abstract

A series of new fluoro S-nitrosothiols is reported as potential nitric oxide (NO) donors. A three-step synthesis and the NO releasing kinetic profiles of these species are presented. The stoichiometric release of NO, with the clean formation of corresponding disulfides, confirms that these new species can facilitate their application as NO donors for various applications including creating novel antimicrobial and thromboresistant fluoropolymer-based medical devices.

Graphical abstract: Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols

Supplementary files

Article information

Article type
Communication
Submitted
07 Nov 2018
Accepted
04 Dec 2018
First published
04 Dec 2018

Chem. Commun., 2019,55, 401-404

Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols

Y. Zhou, J. Tan, Y. Dai, Y. Yu, Q. Zhang and M. E. Meyerhoff, Chem. Commun., 2019, 55, 401 DOI: 10.1039/C8CC08868C

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