Issue 23, 2019

Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Abstract

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.

Graphical abstract: Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Supplementary files

Article information

Article type
Communication
Submitted
12 Jul 2019
Accepted
30 Sep 2019
First published
02 Oct 2019

Analyst, 2019,144, 6850-6857

Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

A. H. C. Anthis, E. Tsolaki, L. Didierlaurent, S. Staubli, R. Zboray, A. Neels, D. Dietrich, P. Manser, L. M. Desbiolles, S. Leschka, S. Wildermuth, S. Lehner, P. Chavatte-Palmer, W. Jochum, P. Wick, A. Dommann, T. Bürki-Turnherr, T. Fischer, R. Hornung, S. Bertazzo and I. K. Herrmann, Analyst, 2019, 144, 6850 DOI: 10.1039/C9AN01312A

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