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Issue 22, 2018
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Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

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Abstract

Herein, we demonstrate a novel, facile, and suitable strategy for imaging GSH based on mercaptopyrimidine-directed gold nanoclusters (Au NCs). GSH can specifically induce the fluorescence enhancement of Au NCs by attacking the surface of the NCs to form dual ligand stabilized Au NCs at the millimolar level. Very importantly, the Au NCs can selectively image cancer cells.

Graphical abstract: Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

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Publication details

The article was received on 23 Mar 2018, accepted on 16 May 2018 and first published on 16 May 2018


Article type: Communication
DOI: 10.1039/C8TB00791H
Citation: J. Mater. Chem. B, 2018,6, 3650-3654
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    Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

    Y. Zheng, W. Liu, Y. Chen, H. Jiang and X. Wang, J. Mater. Chem. B, 2018, 6, 3650
    DOI: 10.1039/C8TB00791H

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