Jump to main content
Jump to site search


Facile preparation of polysaccharide-based sponges and their potential application in wound dressing

Author affiliations

Abstract

Wound exudate adsorption and blood clotting are of critical importance for promoting wound healing in diabetic patients. In this study, cellulose–chitosan hybrid sponges were prepared by a facile pathway with controllable structure and morphology. Aimed at wound dressing, the physical properties, cytocompatibility, and hemocompatibility of the cellulose–chitosan hybrid sponges were evaluated. The results indicated that the hybrid sponges were non-toxic and outperformed silicon in promoting blood coagulation. The sponges could also effectively adsorb abundant wound exudate due to their highly porous structure. Moreover, the maximal shape recovery of these chemically crosslinked sponges from a 50% compression strain was up to 95% of their original thickness, without obviously compromising their macro/microstructure and mechanical properties after 10 cycles. The superior blood coagulation, adsorption performance, and shape recovery properties of the sponges make them ideal for use in making wound dressings for diabetic patients.

Graphical abstract: Facile preparation of polysaccharide-based sponges and their potential application in wound dressing

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Nov 2017, accepted on 02 Jan 2018 and first published on 02 Jan 2018


Article type: Paper
DOI: 10.1039/C7TB03000B
Citation: J. Mater. Chem. B, 2018, Advance Article
  •   Request permissions

    Facile preparation of polysaccharide-based sponges and their potential application in wound dressing

    H. Cheng, C. Li, Y. Jiang, B. Wang, F. Wang, Z. Mao, H. Xu, L. Wang and X. Sui, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C7TB03000B

Search articles by author

Spotlight

Advertisements