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Research progresses on the functional polypeptides in the detection and imaging of breast cancer

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Abstract

Breast cancer is a serious threat to the health of women all over the world. The precise diagnosis and treatment of breast cancer are of great importance to control the development of breast cancer as well as to improve survival rates of the patients. Nowadays, polypeptides are widely applied in breast cancer-related research, benefiting from lower immunogenicity, better biodegradability, higher penetration, and easier synthesis and modification. In this review, we have summarized recent applications of functional polypeptides in the detection and imaging of breast cancer, in which polypeptides work not only as a recognition element and signal source for detecting and imaging breast tumours, but also a building block and a therapeutic drug to assist image-guided treatment of breast cancer.

Graphical abstract: Research progresses on the functional polypeptides in the detection and imaging of breast cancer

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Publication details

The article was received on 22 Sep 2017, accepted on 25 Oct 2017 and first published on 25 Oct 2017


Article type: Review Article
DOI: 10.1039/C7TB02541F
Citation: J. Mater. Chem. B, 2018, Advance Article
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    Research progresses on the functional polypeptides in the detection and imaging of breast cancer

    J. Zhao, H. Chen, Y. Tang, H. Chen, G. Chen, Y. Yin and G. Li, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C7TB02541F

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