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Recent progress in upconversion luminescence nanomaterials for biomedical applications

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Abstract

Upconversion nanoparticles (UCNPs) are one kind of luminescence nanomaterials that convert low energy photons to high energy emissions. These nanomaterials have recently attracted enormous attention due to their unique photophysical properties, such as resistance to photobleaching and photoblinking, low background autofluorescence, and long luminescence lifetime. Owing to these unique advantages, UCNPs have been widely examined for biomedical applications, including biosensing, imaging, and theranostics. In this review, we have first summarized the mechanisms for three generally accepted upconversion luminescence processes, i.e., lanthanide (Ln) doped upconversion luminescence, dye-sensitized upconversion, and triplet–triplet annihilation upconversion, and then discussed recent advancements on the preparation, functionalization, and biomedical applications of each type of UCNPs. The review article finally concludes with our perspectives on UCNPs’ emerging and potential biomedical applications in the near future.

Graphical abstract: Recent progress in upconversion luminescence nanomaterials for biomedical applications

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Publication details

The article was received on 21 Sep 2017, accepted on 27 Nov 2017 and first published on 27 Nov 2017


Article type: Review Article
DOI: 10.1039/C7TB02527K
Citation: J. Mater. Chem. B, 2018, Advance Article
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    Recent progress in upconversion luminescence nanomaterials for biomedical applications

    C. Duan, L. Liang, L. Li, R. Zhang and Z. P. Xu, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C7TB02527K

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