Jump to main content
Jump to site search

Issue 7, 2018
Previous Article Next Article

An injectable supramolecular hydrogel hybridized with silver nanoparticles for antibacterial application

Author affiliations

Abstract

Silver nanoparticles (AgNPs) show long-lasting and broad-spectrum antibacterial activity. Herein, PEGylated AgNPs were prepared in situ by complexing AgNO3 with the random copolymer of poly(ethylene glycol) methyl ether methacrylate (PEGMA) and polyacrylic acid via electrostatic interaction followed by in situ reduction. AgNP hybrid supramolecular hydrogels were thus prepared through host–guest inclusion between PEGMA side chains and α-cyclodextrins in aqueous solution. The hydrogels were physically cross-linked by both pseudopolyrotaxane crystallization and AgNPs, which showed temperature responsiveness and self-healing properties. By hybridizing AgNPs, the hydrogels showed excellent antibacterial properties against S. aureus and E. coli bacteria as well as low cytotoxicity and have potential applications as injectable antibacterial materials.

Graphical abstract: An injectable supramolecular hydrogel hybridized with silver nanoparticles for antibacterial application

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Nov 2017, accepted on 03 Jan 2018 and first published on 04 Jan 2018


Article type: Paper
DOI: 10.1039/C7SM02251D
Citation: Soft Matter, 2018,14, 1227-1234
  •   Request permissions

    An injectable supramolecular hydrogel hybridized with silver nanoparticles for antibacterial application

    Y. Niu, T. Guo, X. Yuan, Y. Zhao and L. Ren, Soft Matter, 2018, 14, 1227
    DOI: 10.1039/C7SM02251D

Search articles by author

Spotlight

Advertisements