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Enantioselective cellular localisation of europium(III) coordination complexes

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Abstract

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

Graphical abstract: Enantioselective cellular localisation of europium(iii) coordination complexes

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Publication details

The article was received on 12 Oct 2017, accepted on 06 Dec 2017 and first published on 06 Dec 2017


Article type: Edge Article
DOI: 10.1039/C7SC04422D
Citation: Chem. Sci., 2018, Advance Article
  • Open access: Creative Commons BY license
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    Enantioselective cellular localisation of europium(III) coordination complexes

    A. T. Frawley, Holly V. Linford, M. Starck, R. Pal and D. Parker, Chem. Sci., 2018, Advance Article , DOI: 10.1039/C7SC04422D

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