Jump to main content
Jump to site search


Challenges and opportunities for alkane functionalisation using molecular catalysts

Author affiliations

Abstract

The conversion of vast low-value saturated hydrocarbons into valuable chemicals is of great interest. Thanks to the progression of organometallic and coordination chemistry, transition metal catalysed C sp3–H bond functionalisation has now become a powerful tool for alkane transformations. Specifically, methods for alkane functionalisation include radical initiated C–H functionalisation, carbene/nitrene insertion, and transition metal catalysed C–H bond activation. This perspective provides a systematic and concise overview of each protocol, highlighting the factors that govern regioselectivity in these reactions. The challenges of the existing catalytic tactics and future directions for catalyst development in this field will be presented.

Graphical abstract: Challenges and opportunities for alkane functionalisation using molecular catalysts

Back to tab navigation

Publication details

The article was received on 17 Aug 2017, accepted on 07 Nov 2017 and first published on 09 Nov 2017


Article type: Perspective
DOI: 10.1039/C7SC03610H
Citation: Chem. Sci., 2018, Advance Article
  • Open access: Creative Commons BY license
  •   Request permissions

    Challenges and opportunities for alkane functionalisation using molecular catalysts

    X. Tang, X. Jia and Z. Huang, Chem. Sci., 2018, Advance Article , DOI: 10.1039/C7SC03610H

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements