Issue 15, 2018, Issue in Progress
From the journal:

RSC Advances

Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices†

Jae Young Kim, ORCID logo a   Eun Seok Seo,a   Hee Jin Lim,a   Hyunmin Kim, ORCID logo b   Ji-Won Park,c   Hyeon Ho Shin,d   Dong-Kwon Lim ORCID logo *d  and  Dae Won Moon*a  

* Corresponding authors

a Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea
E-mail: dwmoon@dgist.ac.kr

b Companion Diagnostics and Medical Technology Research Group, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea

c Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, Republic of Korea

d KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea
E-mail: dklim@korea.ac.kr

Abstract

Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.

Graphical abstract: Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

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Article information

DOI
https://doi.org/10.1039/C8RA00038G
Article type
Paper
Submitted
02 Jan 2018
Accepted
12 Feb 2018
First published
20 Feb 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 8021-8025

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Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

J. Y. Kim, E. S. Seo, H. J. Lim, H. Kim, J. Park, H. H. Shin, D. Lim and D. W. Moon, RSC Adv., 2018, 8, 8021 DOI: 10.1039/C8RA00038G

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