Jump to main content
Jump to site search

Issue 3, 2018, Issue in Progress
Previous Article Next Article

Silica gel-immobilized multidisciplinary materials applicable in stereoselective organocatalysis and HPLC separation

Author affiliations

Abstract

In this pilot study, we present novel bifunctional silica gel-immobilized materials applicable as heterogeneous organocatalysts and stationary phases in HPLC. The materials provided high stereoselectivity in both batch and continuous flow catalysis of a model Michael addition (cyclohexanone to (E)-β-nitrostyrene). In the batch reaction, the catalysts proved their sustainable catalytic activity over five consecutive recycling experiments. Under continuous flow reaction conditions, the catalytic activity was found to be superior to the batch reaction, and moreover, the same immobilized materials were utilized as stationary phases in HPLC showing very good chemoselective separation of model acidic analytes.

Graphical abstract: Silica gel-immobilized multidisciplinary materials applicable in stereoselective organocatalysis and HPLC separation

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Nov 2017, accepted on 20 Dec 2017 and first published on 03 Jan 2018


Article type: Paper
DOI: 10.1039/C7RA12658A
Citation: RSC Adv., 2018,8, 1174-1181
  • Open access: Creative Commons BY license
  •   Request permissions

    Silica gel-immobilized multidisciplinary materials applicable in stereoselective organocatalysis and HPLC separation

    J. Tůma and M. Kohout, RSC Adv., 2018, 8, 1174
    DOI: 10.1039/C7RA12658A

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements