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One Pot Preparation of α-Dithioacetal/α-Diselenoacetal Amides via Cascade Dual-C-S/C-Se Bond Formation and C-C Bond Cleavage of 3-Oxo-Butanamides

Abstract

A renew and practical access to α-dithioacetal/α-diselenoacetal amides has been developed, in combination of sequential functionalization of amides and C-C bond cleavage strategy. In this reaction, various α-dithioacetal/α-diselenoacetal amides containing the primary and secondary ones were prepared in one step with good regioselectivity and functional group tolerance.

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Publication details

The article was received on 28 Apr 2018, accepted on 12 Jun 2018 and first published on 13 Jun 2018


Article type: Research Article
DOI: 10.1039/C8QO00435H
Citation: Org. Chem. Front., 2018, Accepted Manuscript
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    One Pot Preparation of α-Dithioacetal/α-Diselenoacetal Amides via Cascade Dual-C-S/C-Se Bond Formation and C-C Bond Cleavage of 3-Oxo-Butanamides

    J. Zou, Y. Wang, L. Huang, Y. Jiang, J. H. Chen, L. Zhu, Y. Yang, Y. Feng, X. Peng and Z. Wang, Org. Chem. Front., 2018, Accepted Manuscript , DOI: 10.1039/C8QO00435H

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