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Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids

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Abstract

A directing group promoting the cyclopropanation of indoles with 2-furylcarbenoids has been developed. These carbenes are derived from enynones and cost-effective ZnI2 is employed as the catalyst for the efficient construction of various polycyclic compounds under mild reaction conditions.

Graphical abstract: Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids

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Publication details

The article was received on 05 Mar 2018, accepted on 29 Mar 2018 and first published on 30 Mar 2018


Article type: Research Article
DOI: 10.1039/C8QO00232K
Citation: Org. Chem. Front., 2018, Advance Article
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    Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids

    W. Chen, D. Ji, Y. Luo, Z. Wang and P. Xu, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C8QO00232K

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