Jump to main content
Jump to site search

Issue 9, 2018
Previous Article Next Article

Total synthesis of C19-diterpenoid alkaloid: construction of a functionalized ABCDE-ring system

Author affiliations

Abstract

A synthetic approach for the ABCDE ring system of methyllycaconitine starting from a BCD tricycle precursor 14 was described. The synthesis features a useful strategy for the full functionalization of ring B, a 1,7-enyne reductive radical cyclization for the construction of ring A, and a straightforward double condensation for installation of the piperidine ring E.

Graphical abstract: Total synthesis of C19-diterpenoid alkaloid: construction of a functionalized ABCDE-ring system

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Feb 2018, accepted on 14 Mar 2018 and first published on 15 Mar 2018


Article type: Research Article
DOI: 10.1039/C8QO00143J
Citation: Org. Chem. Front., 2018,5, 1502-1505
  •   Request permissions

    Total synthesis of C19-diterpenoid alkaloid: construction of a functionalized ABCDE-ring system

    M. Liu, C. Cheng, W. Xiong, H. Cheng, J. Wang and L. Xu, Org. Chem. Front., 2018, 5, 1502
    DOI: 10.1039/C8QO00143J

Search articles by author

Spotlight

Advertisements