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A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

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Abstract

An efficient and straightforward protocol to complex indene-based polycyclic compounds via the cascade cyclization of propargylic alcohols and alkenes was developed. The catalyst FeCl3, as an Earth-abundant and environment friendly transition metal salt, is attractive. This reaction proceeded through unusual C–C bond cleavage.

Graphical abstract: A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

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Publication details

The article was received on 03 Jan 2018, accepted on 23 Jan 2018 and first published on 24 Jan 2018


Article type: Research Article
DOI: 10.1039/C8QO00004B
Citation: Org. Chem. Front., 2018, Advance Article
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    A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

    X. Su, P. Wu, W. Liu and C. Chen, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C8QO00004B

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