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Issue 7, 2018
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Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

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Abstract

A de novo asymmetric total synthesis of (−)-curcumol has been realized, based on a rhodium-catalyzed cyclization–cycloaddition cascade reaction as the key step to construct the tricyclic nucleus.

Graphical abstract: Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

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Publication details

The article was received on 23 Dec 2017, accepted on 23 Jan 2018 and first published on 23 Jan 2018


Article type: Research Article
DOI: 10.1039/C7QO01150D
Citation: Org. Chem. Front., 2018,5, 1092-1095
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    Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

    X. X. Zhang, R. Y. Y. Ko, X. Q. Xie, W. P. Qi, P. C. Li and P. Chiu, Org. Chem. Front., 2018, 5, 1092
    DOI: 10.1039/C7QO01150D

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