Jump to main content
Jump to site search


Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(I) catalyst

Author affiliations

Abstract

We report a concise, versatile, and practical method for PhI(OCOCF3)2 mediated direct meta-C–H monohalogenation of 2-phenylpyridine and its derivatives via an Ru(I)-catalyzed reaction. The significant advantage of this transformation is the creation of a highly site-selective C–X bond by using NXS as halogenating agents under mild reaction conditions.

Graphical abstract: Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(i) catalyst

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Dec 2017, accepted on 19 Jan 2018 and first published on 26 Jan 2018


Article type: Research Article
DOI: 10.1039/C7QO01133D
Citation: Org. Chem. Front., 2018, Advance Article
  •   Request permissions

    Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(I) catalyst

    G. M. Reddy, N. S. Rao and H. Maheswaran, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C7QO01133D

Search articles by author

Spotlight

Advertisements