Issue 7, 2018
From the journal:

Organic Chemistry Frontiers

Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(i) catalyst†

Ganapam Manohar Reddy, ORCID logo a   Naidu Sambasiva Raoa  and  H. Maheswaran ORCID logo *a  

* Corresponding authors

a Inorganic & Physical Chemistry Division, CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad, India
E-mail: maheswaran_dr@yahoo.com

Abstract

We report a concise, versatile, and practical method for PhI(OCOCF3)2 mediated direct meta-C–H monohalogenation of 2-phenylpyridine and its derivatives via an Ru(I)-catalyzed reaction. The significant advantage of this transformation is the creation of a highly site-selective C–X bond by using NXS as halogenating agents under mild reaction conditions.

Graphical abstract: Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(i) catalyst

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7QO01133D
Article type
Research Article
Submitted
19 Dec 2017
Accepted
19 Jan 2018
First published
26 Jan 2018

Org. Chem. Front., 2018,5, 1118-1123

Permissions

Request permissions

Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(I) catalyst

G. M. Reddy, N. S. Rao and H. Maheswaran, Org. Chem. Front., 2018, 5, 1118 DOI: 10.1039/C7QO01133D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements