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Issue 7, 2018
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A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines

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Abstract

An efficient and stereoselective method for the synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines through a silver-catalyzed three-component reaction of enynals/enynimines, alkenes and H2O via a stabilized cation intermediate has been developed.

Graphical abstract: A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines

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Publication details

The article was received on 16 Dec 2017, accepted on 23 Jan 2018 and first published on 24 Jan 2018


Article type: Research Article
DOI: 10.1039/C7QO01122A
Citation: Org. Chem. Front., 2018,5, 1160-1164
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    A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines

    H. Luo, R. Liang, L. Chen, H. Jiang and S. Zhu, Org. Chem. Front., 2018, 5, 1160
    DOI: 10.1039/C7QO01122A

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