Jump to main content
Jump to site search

Issue 7, 2018
Previous Article Next Article

Cobalt-catalyzed asymmetric reactions of heterobicyclic alkenes with in situ generated organozinc halides

Author affiliations

Abstract

A general strategy for the asymmetric allylation and benzylation of heterobicyclic alkenes is described by employing in situ generated organozinc halides. This methodology features the application of a co-catalytic system comprising chiral cobalt complex and Lewis acid, which deliver both the asymmetric ring opening products of oxabenzonorbornadienes and the asymmetric addition products of azabenzonorbornadienes, respectively.

Graphical abstract: Cobalt-catalyzed asymmetric reactions of heterobicyclic alkenes with in situ generated organozinc halides

Back to tab navigation

Supplementary files

Publication details

The article was received on 28 Nov 2017, accepted on 22 Dec 2017 and first published on 22 Dec 2017


Article type: Research Article
DOI: 10.1039/C7QO01064H
Citation: Org. Chem. Front., 2018,5, 1108-1112
  •   Request permissions

    Cobalt-catalyzed asymmetric reactions of heterobicyclic alkenes with in situ generated organozinc halides

    Y. Li, J. Chen, Z. He, H. Qin, Y. Zhou, R. Khan and B. Fan, Org. Chem. Front., 2018, 5, 1108
    DOI: 10.1039/C7QO01064H

Search articles by author

Spotlight

Advertisements